Datum der Indexierung 03.05.2024 22:10:02
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Kombination Keywords gene lack | retinal your | light particles | clinical reactions | therapy vision | that inherited | cells test | visual viral | patient protein | into this |
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protein. RPE65 and the visual cycle The RPE65 protein is an enzyme that plays an essential role in the visual cycle, a sequence of biochemical reactions in the retina that are required for vision. In response to light, 11-cis-retinal, a small molecul regeneration of all-trans-retinal into 11-cis-retinal. RPE65 is one of the proteins required for that regeneration. Gene mutations affecting RPE65 function will block regeneration of 11-cis-retinal. Consequently, the visual cycle,
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