3 Einträge von 3 mit receptor region
clinicalodyssey.com
Datum der Indexierung 03.05.2024 22:10:10
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Kombination Keywords cells chimeric | cell genetic | malignant t-cells | plasma patient | multiple therapies | myeloma bcma | antigen these | against with | rrmm their | from clinical |
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receptor T-cell (CAR-T) therapies, which utilize genetically modified T-cells from the same patient to find and destroy malignant cells carrying a specific molecule on their surface. CAR-T cell therapies against RRMM In CAR-T therapies, T-cells are o region, and an extracellular region that recognizes t he B-cell maturation antigen (BCMA) . The 4-1BB and CD3-zeta molecules have co-stimulatory and signaling functions, respectively, promoting T-cell fitness, expansion, and activ
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Kombination Keywords cells chimeric | cell genetic | malignant t-cells | plasma patient | multiple therapies | myeloma bcma | antigen these | against with | rrmm their | from clinical |
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receptor T-cell (CAR-T) therapies, which utilize genetically modified T-cells from the same patient to find and destroy malignant cells carrying a specific molecule on their surface. CAR-T cell therapies against RRMM In CAR-T therapies, T-cells are o region, and an extracellular region that recognizes t he B-cell maturation antigen (BCMA) . The 4-1BB and CD3-zeta molecules have co-stimulatory and signaling functions, respectively, promoting T-cell fitness, expansion, and activ
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clinicalodyssey.com
Datum der Indexierung 03.05.2024 22:10:12
erkannte Namen Gene Therapy |
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Kombination Keywords cell medical | cells effects | receptor your | antigen region | chimeric about | b-cell therapy | clinical from | t-cell this | patient immunotherapy | lymphoma b-cells |
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receptor The T-cell chimeric antigen receptor is a transmembrane fusion protein with an extracellular region binding the target antigen. CD19, a protein located on the surface of human B-cells, is one of the most targeted antigens. It is a convenient region binding the target antigen. CD19, a protein located on the surface of human B-cells, is one of the most targeted antigens. It is a convenient recognition element for these cells—particularly when they are abundant due to un
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erkannte Namen Gene Therapy |
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Kombination Keywords cell medical | cells effects | receptor your | antigen region | chimeric about | b-cell therapy | clinical from | t-cell this | patient immunotherapy | lymphoma b-cells |
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receptor The T-cell chimeric antigen receptor is a transmembrane fusion protein with an extracellular region binding the target antigen. CD19, a protein located on the surface of human B-cells, is one of the most targeted antigens. It is a convenient region binding the target antigen. CD19, a protein located on the surface of human B-cells, is one of the most targeted antigens. It is a convenient recognition element for these cells—particularly when they are abundant due to un
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clinicalodyssey.com
Datum der Indexierung 03.05.2024 22:10:04
erkannte Namen Gene Therapy |
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Kombination Keywords cell marrow | cells bone | b-cell genetic | b-all have | receptor this | gene therapy | chimeric precursors | from patient | t-cells antigen | with these |
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receptor. After genetic modification and proliferation, T-cells are returned to the bloodstream of the patient. In the patient, these T-cells produce and display on their surface a chimeric antigen receptor that recognizes the CD19 protein on the sur region is densely innervated, has excellent blood supply, and is rich in regulatory molecules. Due to their critical role in B-cell differentiation, cells from the bone marrow microenvironment can also contribute to the developmen
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erkannte Namen Gene Therapy |
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Kombination Keywords cell marrow | cells bone | b-cell genetic | b-all have | receptor this | gene therapy | chimeric precursors | from patient | t-cells antigen | with these |
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receptor. After genetic modification and proliferation, T-cells are returned to the bloodstream of the patient. In the patient, these T-cells produce and display on their surface a chimeric antigen receptor that recognizes the CD19 protein on the sur region is densely innervated, has excellent blood supply, and is rich in regulatory molecules. Due to their critical role in B-cell differentiation, cells from the bone marrow microenvironment can also contribute to the developmen
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